Immunosuppression of spleen in mice treated with erythropoietin: transcriptomic and immunological analysis
Background and aimLong term high-dose erythropoietin (EPO) had been reported inducing the formation of abdominal aortic aneurysm (AAA) in mice.When using this model, we found that EPO treated mice showed significant splenomegaly.This is an interesting phenomenon, and its mechanism has not been reported.Therefore, this study aims to explore its mech